Iams, MD: Small cell lung cancer typically shrinks with initial chemotherapy. Two out of 3 or more patients who are first diagnosed with small cell lung cancer have tumor shrinkage when they’re treated with standard chemotherapy.
Is small cell lung cancer sensitive to chemotherapy?
Small cell lung cancer is different from other lung cancer histologic types in that it has neuroendocrine features, grows more rapidly, spreads earlier, is more responsive to chemotherapy and radiotherapy, and has a lower cure rate.
Does Chemo shrink lung tumors?
Chemo for SCLC
Up to 15% of people with lung cancer have small-cell lung cancer. If your SCLC is at a limited stage, you’ll get chemotherapy and radiation therapy together to shrink your tumor. If your SCLC is at an extensive stage and has spread, you’ll get chemotherapy alone.
How long does chemo prolong life in small cell lung cancer?
Chemotherapy (chemo) may prolong life in some lung cancer patients. According to a study reported in the Journal of the American Medical Association that looked at the role of chemotherapy at the end of life, chemo for some patients with a specific type of lung cancer prolonged their lives by two to three months.
How successful is chemotherapy for small cell lung cancer?
Chemotherapy with or without immunotherapy still offers a high rate of response, with 60 to 80 percent of patients having significant tumor shrinkage and 10 to 15 percent achieving a complete response. The use of maintenance immunotherapy may prolong treatment response and survival in some people.
How long does chemo take to shrink a tumor?
In general, chemotherapy can take about 3 to 6 months to complete. It may take more or less time, depending on the type of chemo and the stage of your condition. It’s also broken down into cycles, which last 2 to 6 weeks each.
What are the signs that chemo is working?
How Can We Tell if Chemotherapy is Working?
- A lump or tumor involving some lymph nodes can be felt and measured externally by physical examination.
- Some internal cancer tumors will show up on an x-ray or CT scan and can be measured with a ruler.
- Blood tests, including those that measure organ function can be performed.
What is the survival rate for chemotherapy?
The survival rate for those diagnosed in stages 1-3 is near 100% and about 71% for stage 4. The five-year survival rate is 90% for medullary carcinoma and 7% for anaplastic carcinoma.
How many times can you have chemo for small cell lung cancer?
Cycles are most often 3 or 4 weeks long, and initial treatment is typically 4 to 6 cycles. The schedule varies depending on the drugs used. For example, some drugs are given only on the first day of the chemo cycle. Others are given for a few days in a row, or once a week.
Does small cell lung cancer go into remission?
Chemotherapy is the keystone in the treatment of small cell lung cancer (SCLC). Objective remission and good palliation is achieved in ∼80% of the patients, but the remissions are in general short (mean <1 yr), and few are cured.
What is the life expectancy of small cell lung cancer?
Small-cell lung cancer (SCLC) is very aggressive. For limited stage SCLC, the five-year survival rate is 14 percent . Median survival is 16 to 24 months. Median survival for extensive stage SCLC is six to 12 months.