Aside from cases of isolated recurrences, such as a vaginal recurrence in a patient with no prior irradiation or a solitary distant metastatic deposit which may be cured by surgical resection, recurrent endometrial cancer is not curable and eventually leads to death.
Is metastatic endometrial cancer curable?
While endometrial cancer is a highly curable malignancy when it presents as a uterine-confined disease, the prognosis for recurrent or metastatic disease is poor. The median survival of women enrolled in trials for recurrent or metastatic endometrial cancer hardly exceeds 12 months .
How is metastatic uterine cancer treated?
Treatment for endometrial cancer is usually with surgery to remove the uterus, fallopian tubes and ovaries. Another option is radiation therapy with powerful energy. Drug treatments for endometrial cancer include chemotherapy with powerful drugs and hormone therapy to block hormones that cancer cells rely on.
Where does endometrial cancer usually metastasize to?
Metastatic uterine (endometrial) cancer is a type of cancer that originated in the lining of the uterus (endometrium) and has spread to distant areas of the body. In general, uterine cancer can metastasize to the rectum or bladder. Other areas where it may spread include the vagina, ovaries and fallopian tubes.
How long can you live with metastatic uterine cancer?
Five-year survival rate was 5.7% (95% confidence interval: 0.0-13.3), and median survival was 7.6 months. Survival of patients with a single metastasis at the time of diagnosis was longer than for patients with multiple metastases (16 versus two months, respectively; p < 0.00 1).
Can uterine cancer come back after hysterectomy?
Endometrial cancer is most likely to recur in the first three years after the initial treatment, though late recurrence is also possible. If you would like to speak with a physician at Moffitt Cancer Center about endometrial cancer or undergoing a hysterectomy, we invite you to request an appointment.
What is the survival rate for stage 4 uterine cancer?
Women with stage IV (4) uterine cancer have a survival rate of about 15%.
What is the most aggressive uterine cancer?
Uterine sarcomas, which develop in the muscle tissue of the uterus (the myometrium). This type is rare, but is also the most aggressive form of uterine cancer.
How long can you live with untreated uterine cancer?
Five other cases of untreated endometrial carcinoma were found in the literature. The patients had varying length of survival (range: 5 months to 12 years), but all patients experienced generally good health several years after diagnosis.
What does it mean when you have stage 4 uterine cancer?
Stage 4 uterine cancer: The cancer has spread to the inner surface of the urinary bladder or the rectum (lower part of the large intestine), to lymph nodes in the groin, and/or to distant organs, such as the bones, omentum or lungs.
What are the symptoms of advanced uterine cancer?
Symptoms of advanced endometrial cancer include abdominal or pelvic pain, bloating, feeling full quickly when eating, and changes in bowel or bladder habits.