Asymptomatic pulmonary tuberculosis (PTB) mimicking lung cancer is rare and has been documented in few studies. Accurately diagnosing this atypical disease remains an enormous challenge for clinicians.
Tuberculosis may increase the risk of lung cancer through substantial and prolonged pulmonary inflammation, leading to host tissue damage, fibrosis, scar formation, and genetic alterations (3–6). A recent meta-analysis reported tuberculosis to be associated with a 1.7-fold elevation in the risk of lung cancer (7).
What can TB be mistaken for?
Results: 1. Diseases, most often initially misdiagnosed as tuberculosis, were pneumonia (52 %), lung cancer (20 %). 2. The period from the disease manifestation up to establishment of final diagnosis was 84 ± 72.8 (mean±SD) days.
Can TB cause mass in lung?
Pulmonary TB can be a cause of nodular, or mass-like, lung opacities in asymptomatic patients whose sputum smears or cultures may be negative for mycobacteria (15). Pulmonary TB is one of the most common benign lesions that requires differentiation from lung cancer (16, 17).
Can latent TB cause lung cancer?
Background: Tuberculosis (TB) appears to be a risk factor for lung cancer, but whether or not it is the cause is still uncertain. Patients with latent TB infection (LTBI) are vulnerable to develop active TB, however, the relationship between lung cancer and LTBI is not well understood.
Can TB convert into cancer?
Tuberculosis is an important risk factor for cancer. The dormant bacilli may activate due to disturbed defense mechanisms. Pulmonary cancer mortality was higher in people with tuberculosis than in those without.
Can TB become cancer?
Briefly, it is assumed that TB is one of the risk factors for cancer. Numerous studies have been conducted in this regard throughout the world and it has been observed that there is a significant relationship between previous TB infection and lung cancer.
Can tuberculosis be misdiagnosed?
In the present study, the incidence of patients with misdiagnosis of TB was around 14.6% with some revised early to obtain a diagnosis of lung cancer (0.7%). We conducted this study to review the patients with initial notification of TB and then diagnosis revision to lung cancer in a TB-prevalent area.
What disease is similar to TB?
There are more than 25 different species of mycobacteria that cause nontuberculous mycobacterial infections. One of the most common is Mycobacterium avium, which can cause symptoms similar to tuberculosis, such as cough, fever, fatigue, and weight loss.
Do lungs heal after TB?
Researchers have found that more than one-third of patients who are successfully cured of TB with antibiotics developed permanent lung damage which, in the worst cases, results in large holes in the lungs called cavities and widening of the airways called bronchiectasis.
Does TB always leave scar lungs?
Following up on tuberculosis treatment and periodic testing of lung functions also help. The findings of the study show that the ill-effects of tuberculosis infection do not perish by merely treating it. The scar once left on the lungs stays throughout and haunts the individual with every breath one takes.
What is the difference between tuberculosis and pulmonary tuberculosis?
The bacterium Mycobacterium tuberculosis causes tuberculosis (TB), a contagious, airborne infection that destroys body tissue. Pulmonary TB occurs when M. tuberculosis primarily attacks the lungs. However, it can spread from there to other organs.
Does TB affect both lungs?
Tuberculosis (TB) is an airborne bacterial infection caused by the organism Mycobacterium tuberculosis that primarily affects the lungs, although other organs and tissues may be involved.