How does Hodgkin lymphoma affect the spleen?

Lymphoma can make your spleen work harder than normal. For example, if your lymphoma causes autoimmune haemolytic anaemia or immune thrombocytopenia, your spleen has to work hard to destroy the antibody-coated red blood cells or platelets.

Can lymphoma spread to the spleen?

Spleen cancer typically develops when cancer in another part of the body, most often lymphomas and leukemia, spread to this fist-sized organ. The spleen is under the rib cage on the left side of the body. It is part of the lymphatic system and plays a part in helping the body fight off disease.

How does Hodgkin’s lymphoma affect the organs?

In Hodgkin lymphoma, B-lymphocytes (a particular type of lymphocyte) start to multiply in an abnormal way and begin to collect in certain parts of the lymphatic system, such as the lymph nodes (glands). The affected lymphocytes lose their infection-fighting properties, making you more vulnerable to infection.

How does non-Hodgkin lymphoma affect the spleen?

Splenic marginal zone lymphoma (SMZL) is a slow-growing (indolent) B-cell non-Hodgkin lymphoma (NHL). It usually affects the spleen, bone marrow and blood. It can sometimes affect lymph nodes in the abdomen, but in most cases SMZL doesn’t affect lymph nodes. Inflammation of the liver.

THIS IS IMPORTANT:  Your question: Does flat poop always mean cancer?

What stage is lymphoma in the spleen?

Stages of non-Hodgkin lymphoma may also include E and S. “E” stands for extranodal, and means the cancer is found in an area or organ other than the lymph nodes or has spread to tissues beyond, but near, the major lymphatic areas. “S” stands for spleen and means the cancer is found in the spleen.

How does lymphoma affect spleen?

The spleen may become bigger if lymphoma cells build up there. This is called splenomegaly. It can cause discomfort or pain in the upper part of the tummy. Some people with SMZL will have a low number of blood cells in their blood.

Is the spleen enlarged with lymphoma?

Lymphoma and the spleen

An enlarged spleen (also called ‘splenomegaly’) can occur in several types of lymphoma, including Hodgkin lymphoma, chronic lymphocytic leukaemia, diffuse large B-cell lymphoma, mantle cell lymphoma, hairy cell leukaemia, splenic marginal zone lymphoma, and Waldenström’s macroglobulinaemia.

What are the organs commonly affected by Hodgkin’s disease?

If Hodgkin lymphoma spreads, the most common locations where it spreads are the lung, spleen, liver, bone marrow, or bone. Hodgkin lymphoma can spread to other parts of the body, but this is unusual.

Where does lymphoma spread to first?

Lymphoma most often spreads to the liver, bone marrow, or lungs. People of any age can develop lymphoma, but it is among the most common causes of cancer in children and young adults aged 15–24 years.

What organs does lymphoma affect?

Lymphoma is a cancer of the lymphatic system, which is part of the body’s germ-fighting network. The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. Lymphoma can affect all those areas as well as other organs throughout the body.

THIS IS IMPORTANT:  How do you know if you have a tumor in your nose?

What cancers affect the spleen?

Spleen cancers are typically secondary, meaning that they originate elsewhere and then spread to the spleen. The most common causes of spleen cancer are lymphomas and leukemias. On occasion, other cancers, such as breast, lung, stomach, pancreatic, liver, or colon, are the source of the malignancy.

What are the symptoms of spleen problems?


  • Pain or fullness in the left upper belly that can spread to the left shoulder.
  • A feeling of fullness without eating or after eating a small amount because the spleen is pressing on your stomach.
  • Low red blood cells (anemia)
  • Frequent infections.
  • Bleeding easily.

What are warning signs of the spleen?

In any case, emergency medical help is needed quickly. Signs that the spleen may have been damaged can include pain and tenderness in the upper left abdomen, lightheadedness, and pain in the left shoulder. In addition to a spleen that has been damaged or has ruptured, the spleen may also become dangerously enlarged.