Warthin tumor is a relatively frequent and benign neoplasm of the major salivary glands. It is histologically characterized by a dense lymphoid stroma and a double layer of oncocytic epithelium with a papillary and cystic architectural pattern. Its etiology remains uncertain.
Can a warthin tumor be malignant?
The malignant transformation of Warthin’s tumor is extremely rare and occurs in about 0.3% of cases. The transformation of the lymphoid component to a malignant lymphoma appears to occur more frequently than an epithelial malignant transformation, which is extremely rare [3,4].
Is warthin’s tumor common?
Warthin’s tumor is the second most common benign neoplasm of the salivary glands, accounting for 2% to 6% of parotid tumors. In the parotid, it is usually found in the inferior lobe of the gland. This unusual type of tumor is a slow-growing, painless, round-to-ovoid mass.
Should a warthin tumor be removed?
Unlike pleomorphic adenomas, Warthin’s tumor presents less than 1% risk of malignant evolution . That is why surgery is not necessary when the preoperative diagnosis is certain and surgery should be avoided as often as possible because of the risk of facial nerve injury during surgery , .
Are warthin tumors genetic?
The potential genetic predisposition of Warthins tumour, via point mutation and genetic translocation (as mentioned previously), is also supported in all of the cases described, as each case series were direct relatives.
What causes a warthin tumor?
The exact underlying cause of Warthin tumor is currently unknown. However, smoking is thought to increase the risk of developing the tumor. Some studies suggest that radiation exposure and autoimmune disorders may also be associated with Warthin tumor.
What is neoplasm disease?
Neoplastic disease. A neoplasm is an abnormal growth of cells, also known as a tumor. Neoplastic diseases are conditions that cause tumor growth — both benign and malignant. Benign tumors are noncancerous growths. They usually grow slowly and can’t spread to other tissues.
Is warthin tumor bilateral?
Epidemiology. Warthin tumors are the 2nd most common benign parotid tumor (after pleomorphic adenoma) and represent up to 10% of all parotid tumors. They are the commonest bilateral or multifocal benign parotid tumor. They typically occur in the elderly (6th decade), and twice as common in men (2.2:1) 11.
What happens when parotid gland is removed?
Permanent damage is possible but usually occurs in only the most difficult cases. Depending on the branch of the nerve that is damaged you may experience: • Weakness of the lower lip, leading to a slightly crooked smile. Weakness of the eyelids, making it difficult to keep the eye closed.
Do benign parotid tumors have to be removed?
Treatment of Salivary Gland Tumors
If you have a benign tumor, your doctor may recommend surgical removal to prevent it from becoming malignant over time. A benign tumor in the parotid gland can be removed using a surgical procedure called a partial superficial parotidectomy.
How do I get rid of warthin tumor?
Therefore, we recommend that enucleation is a useful choice as a surgical procedure for the removal of Warthin’s tumor after accurate detection of the tumors using MRI. The overall incidences of temporary and permanent facial nerve palsy were 19.7% and 0%, respectively.
How fast does a warthin tumor grow?
Warthin’s tumours appear to have an approximate average doubling time of 9 years, but can have a wide range of growth rates, with many cases showing a reduction in size.
What is a parotid neoplasm?
A salivary gland tumor or parotid tumor is cancer beginning in one of your salivary glands. It’s not just a single disease. You actually have various salivary glands near and inside your mouth. Many types of-cancerous (benign) tumors and cancer can develop in these salivary glands.