Cancer cells are given a grade when they are removed from the breast and checked in the lab. The grade is based on how much the cancer cells look like normal cells. The grade is used to help predict your outcome (prognosis) and to help figure out what treatments might work best.
How do they determine cancer grade?
The grade of a cancer depends on what the cells look like under a microscope. In general, a lower grade indicates a slower-growing cancer and a higher grade indicates a faster-growing one. The grading system that’s usually used is as follows: grade I – cancer cells that resemble normal cells and aren’t growing rapidly.
Is grade 2 breast cancer bad?
Overall, the prognosis for stage 2 breast cancer is generally good. According to the American Cancer Society, the 5-year relative survival rate is: 99 percent for localized breast cancer (has not spread outside the breast) 86 percent for regional breast cancer (spread to nearby lymph nodes)
What is the difference between stages and grades of breast cancer?
Staging means how big the cancer is and whether it has spread. Grading means how abnormal the cancer cells look under a microscope.
What is histologic grade in breast cancer?
One of the best-established prognostic factors in breast cancer is histological grade, which represents the morphological assessment of tumor biological characteristics and has been shown to be able to generate important information related to the clinical behavior of breast cancers.
Is grade 3 breast cancer serious?
A low grade number (grade 1) usually means the cancer is slower-growing and less likely to spread. A high grade number (grade 3) means a faster-growing cancer that’s more likely to spread.
What is invasive ductal carcinoma grade 2?
There are three grades of invasive breast cancer: Grade 1 looks most like normal breast cells and is usually slow growing. Grade 2 looks less like normal cells and is growing faster. Grade 3 looks different to normal breast cells and is usually fast growing.
Does grade 2 breast cancer need chemo?
If you’ve been diagnosed with stage 2 breast cancer, the outlook is very good. You are more likely to have chemotherapy and/or radiation therapy than if your tumor was stage 1, but these tumors are still very treatable.
What is histologic grade?
Listen to pronunciation. (HIS-tuh-LAH-jik grayd) A description of a tumor based on how abnormal the cancer cells and tissue look under a microscope and how quickly the cancer cells are likely to grow and spread.
What does invasive ductal carcinoma grade 3 mean?
Grade 1 invasive ductal carcinoma cells, which are sometimes called “well differentiated,” look and act somewhat like healthy breast cells. Grade 3 cells, also called “poorly differentiated,” are more abnormal in their behavior and appearance.
Is grade or stage more important?
The cells are graded by comparing them to normal cells. Low-grade cancers look more like normal tissue under the microscope. High-grade tumors look very abnormal and are generally more aggressive. Staging determines the tumor’s size and whether the cancer has spread to other parts of the body.
Does grade 2 breast cancer come back?
Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence).