What does malignant melanoma arise from?

Malignant Melanoma is a common skin cancer that arises from the melanin cells within the upper layer of the skin (epidermis) or from similar cells that may be found in moles (nevi). This type of skin cancer may send down roots into deeper layers of the skin.

How does melanoma grow?

Melanoma is a type of skin cancer that develops when melanocytes (the cells that give the skin its tan or brown color) start to grow out of control. Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer, and can then spread to other areas of the body.

How do most skin cancers arise?

Skin cancer — the abnormal growth of skin cells — most often develops on skin exposed to the sun. But this common form of cancer can also occur on areas of your skin not ordinarily exposed to sunlight.

What lesions progress to malignant melanoma?

Melanoma also may occur in unexposed areas of the skin, including the palms, soles, and perineum. Certain lesions are considered to be precursor lesions of melanoma. These include the following nevi: Common acquired nevus.

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Where does melanoma usually spread to first?

Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin.

What are the four stages of melanoma?

Overview of Stages O-IV

  • Stage 0 Melanoma (in situ) …
  • Stage I Melanoma (localized tumor) …
  • Stage II Melanoma (localized tumor) …
  • Stage III Melanoma (regional spread) …
  • Stage IV Melanoma (metastasis beyond regional lymph nodes) …
  • Brain Metastases.

What layer of the skin does melanoma start in?

Epidermis – this outer, top skin layer contains mostly flat squamous cells. Under those and deeper in the skin are the basal cells, and scattered among the basal cells are the melanocytes, where melanoma begins.

What epidermal layer does melanoma arise in?

Melanoma starts in cells in the skin called melanocytes. These cells are in the deep layer of the epidermis between the layer of basal cells.

What is the difference between melanoma and carcinoma?

Melanoma typically begins as a mole and can occur anywhere on the body. Squamous cell carcinoma may appear as a firm red bump, a scaly patch, or open sore, or a wart that may crust or bleed easily. Basal cell carcinoma may appear as a small white or flesh-colored bump that grows slowly and may bleed.

Which of the following characteristics is associated with malignant melanoma?

Characteristics/Clinical Presentation

The characteristics of melanoma are commonly known by the acronym ABCDE and include the following: A – Asymmetry. B – Irregular border. C – Color variations, especially red, white, and blue tones in a brown or black lesion.

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What part of the integumentary system does malignant melanoma affect?

Melanoma can develop anywhere on the body, including the head and neck, the skin under the fingernails, the genitals, and even the soles of the feet or palms of the hands. Melanoma may not be colored like a mole. It may have no color or be slightly red, which is called amelanotic melanoma.