What kind of cancer is angiosarcoma?

Angiosarcoma is a rare cancer that develops in the inner lining of blood vessels and lymph vessels. This cancer can occur anywhere in the body but most often is in the skin, breast, liver and spleen.

What is the survival rate for angiosarcoma?

Due to its high aggressiveness and multifocality, the prognosis of angiosarcoma is poor, with a reported five-year survival rate of ~35% in non-metastatic angiosarcoma cases (1,4,6). The majority of cases of recurrence (75%) occur within 24 months of local treatment (1).

Does anyone survive angiosarcoma?

Angiosarcomas are prone to locoregional recurrence, nodal and distant metastases, and have notoriously poor prognoses. The reported rates of advanced/metastatic disease at presentation vary from 16 to 44%, and the overall disease-specific survival is reported as approximately 30–40% in contemporary series.

How long can you live with angiosarcoma?

A few research studies show that the survival time for this type of cancers is 15–20 months. In spite of this, 35% of patients survive up to five years.

What type of tumor is angiosarcoma?

Angiosarcoma is cancer that forms in the lining of blood vessels and lymph vessels. It often affects the skin and may appear as a bruise-like lesion that grows over time. Angiosarcoma is a rare type of cancer that forms in the lining of the blood vessels and lymph vessels.

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Can you beat angiosarcoma?

Treatment options may include: Surgery. The goal of surgery is to remove the angiosarcoma entirely. Your surgeon will remove the cancer and some of the healthy tissue that surrounds it.

How do you stage angiosarcoma?

Staging

  1. Stage 1 means the cancer is low grade, small (less than 5cm) and has not spread to other parts of the body.
  2. Stage 2 means the cancer is of any grade, usually larger than stage one but has not spread to other parts of the body.
  3. Stage 3 means a high grade cancer that has not spread to other parts of the body.

Is angiosarcoma genetic?

Angiosarcoma can sometimes run in families. Scientists have found that people with a change in a gene called POT1 may develop angiosarcoma of the heart, and this change can be passed on to their children.

Is angiosarcoma malignant?

Angiosarcomas are malignant sarcomas of vascular endothelial cell origin. Endothelial cells make up the lining of vessels. Angiosarcomas can occur in any region of the body, although they are most commonly located in the skin, breast, liver, and deep tissue.

Where does angiosarcoma metastasize?

Angiosarcoma primarily spreads haematogenously, with the lungs as the most common site for metastases. Metastases also frequently affect the liver (Figure 8), bones (Figure 2), soft tissues and lymph nodes.

How long can you have sarcoma without knowing?

It would appear that some people are quite happy to live with asymptomatic lumps for up to 5 or more years and our experience shows that most of these patients will have been re-assured by one or more doctors during this time. A long duration of symptoms has been shown to correlate weakly with good prognosis.

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Does sarcoma respond to chemo?

Depending on the type and stage of sarcoma, chemotherapy may be given as the main treatment or as an adjuvant (addition) to surgery. Different types of sarcoma respond better to chemo than others and also respond to different types of chemo.

Does sarcoma spread quickly?

Most stage II and III sarcomas are high-grade tumors. They tend to grow and spread quickly. Some stage III tumors have already spread to nearby lymph nodes. Even when these sarcomas have not yet spread to lymph nodes, the risk of spread (to lymph nodes or distant sites) is very high.