Where does melanoma arise from?

Malignant Melanoma is a common skin cancer that arises from the melanin cells within the upper layer of the skin (epidermis) or from similar cells that may be found in moles (nevi). This type of skin cancer may send down roots into deeper layers of the skin.

Where does melanoma usually start?

Melanomas can develop anywhere on the skin, but they are more likely to start on the trunk (chest and back) in men and on the legs in women. The neck and face are other common sites.

Which cells in the skin do melanoma arise from?

Melanoma is a type of skin cancer. It starts in cells in the skin called melanocytes. There are 2 main categories of skin cancer.

What layer of skin does melanoma start?

Epidermis – this outer, top skin layer contains mostly flat squamous cells. Under those and deeper in the skin are the basal cells, and scattered among the basal cells are the melanocytes, where melanoma begins.

Where is most melanoma found?

Melanomas can develop anywhere on your body. They most often develop in areas that have had exposure to the sun, such as your back, legs, arms and face. Melanomas can also occur in areas that don’t receive much sun exposure, such as the soles of your feet, palms of your hands and fingernail beds.

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What does Stage 1 melanoma look like?

Stage I melanoma is no more than 1.0 millimeter thick (about the size of a sharpened pencil point), with or without an ulceration (broken skin). There is no evidence that Stage I melanoma has spread to the lymph tissues, lymph nodes, or body organs.

Do melanomas appear suddenly?

Melanoma may suddenly appear without warning, but can also develop from or near an existing mole. It can occur anywhere on the body, but is most common on the upper back, torso, lower legs, head, and neck.

Is melanoma dominant or recessive?

In fair-complexioned individuals worldwide, the majority of melanoma cases are related to environmental factors such as excessive ultraviolet radiation (sun exposure). However, about 5-10% of melanoma cases are inherited in an autosomal dominant fashion.

Do melanomas itch?

Some melanomas itch. The “E” in the ABCDE rule of melanoma is for “Evolving,” which means that something about the mole changes. New itching or tenderness falls under “Evolving.” So does a change in the size, shape, color or elevation of the mole. A melanoma may also begin to bleed or crust over.

Are melanomas painful?

You can have melanoma without feeling any pain or discomfort. For many people, the only sign of this skin cancer is a spot that has some of the ABCDEs of melanoma or a line beneath a nail. Sometimes, melanoma causes discomfort.

What does a melanoma spot look like?

Border that is irregular: The edges are often ragged, notched, or blurred in outline. The pigment may spread into the surrounding skin. Color that is uneven: Shades of black, brown, and tan may be present. Areas of white, gray, red, pink, or blue may also be seen.

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Can you have melanoma for years and not know?

How long can you have melanoma and not know it? It depends on the type of melanoma. For example, nodular melanoma grows rapidly over a matter of weeks, while a radial melanoma can slowly spread over the span of a decade. Like a cavity, a melanoma may grow for years before producing any significant symptoms.

How do you feel with melanoma?

Symptoms of advanced melanoma

  • hard or swollen lymph nodes.
  • hard lump on your skin.
  • unexplained pain.
  • feeling very tired or unwell.
  • unexplained weight loss.
  • yellowing of eyes and skin (jaundice)
  • build up of fluid in your tummy (abdomen) – ascites.
  • tummy pain.

Can you live a long life with melanoma?

Life expectancy for cancers is often expressed as a 5-year survival rate (the percent of patients who will be alive 5 years after diagnosis). The overall average 5-year survival rate for all patients with melanoma is 92%. This means 92 of every 100 people diagnosed with melanoma will be alive in 5 years.

Are skin cancers itchy?

Skin cancers often don’t cause bothersome symptoms until they have grown quite large. Then they may itch, bleed, or even hurt. But typically they can be seen or felt long before they reach this point.

Can black people get melanoma?

Overall, skin cancer is less common in Black people. Data from the Centers for Disease Control and Prevention (CDC) found that in 2018 (the most recent data we have available), 1 case of melanoma occurred per 100,000 Black people, compared with 25 cases per 100,000 white people.

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