Your question: How accurate is AFP test for cancer?

Levels of AFP >20 ng/mL detected HCC with 70.1% sensitivity and 89.8% specificity. This AFP level identified patients with HCC with a c-statistic of 0.87 (95% confidence interval, 0.85–0.89); it was significantly more accurate in HCV-negative patients than HCV-positive patients (c-statistic 0.89 vs 0.83; P=. 007).

What cancer does AFP detect?

If your results show high levels of AFP, it may confirm a diagnosis of liver cancer, or cancer of the ovaries or testicles. Sometimes, high levels of AFP can be a sign of other cancers, including Hodgkin disease and lymphoma, or noncancerous liver disorders.

Can you have liver cancer with a normal AFP?

Many patients with early liver cancer have normal AFP levels. Also, AFP levels can be increased from other kinds of cancer as well as some non-cancerous conditions.

Can AFP levels fluctuate?

Fluctuations in serum AFP levels within the normal range occur in patients during this follow-up period, causing anxiety about relapse. Patients frequently question the significance of an increase in AFP within normal levels and whether it predicts for relapse.

THIS IS IMPORTANT:  What are the two most common malignant bone tumors of childhood quizlet?

What is an abnormal AFP result?

What do the results mean? If your results show higher than normal AFP levels, it may mean your baby has a neural tube defect such as spina bifida, a condition in which the bones of the spine don’t close around the spinal cord, or anencephaly, a condition in which the brain does not develop properly.

What is considered a high tumor marker?

Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

Can fatty liver cause elevated AFP?

Conclusion. Patients with NAFLD have higher AFP levels than those without fatty liver changes. AFP levels rise as grade of liver steatosis increases. NAFLD should be among the differential diagnosis of elevated serum AFP levels.

How long does it take for liver cancer to show symptoms?

Liver cancer does not usually cause symptoms until the tumor has grown large, pushing against other parts of the liver or other organs. But it can take months or even years for that to happen.

Would liver cancer show up in blood work?

Liver cancer is not detected by blood tests alone. Liver cancer is not detected by blood tests alone. Certain substances present in the blood called the blood markers may be elevated in patients with liver cancer.

Can you see liver cancer on a CT scan?

A CT scan of the abdomen can help find many types of liver tumors. It can give specific information about the size, shape, and location of any tumors in the liver or elsewhere in the abdomen, as well as nearby blood vessels.

THIS IS IMPORTANT:  Can you have chemo if you've had a kidney transplant?

What does it mean if tumor markers go up?

Tumor markers are most often used to track how a patient’s cancer responds to treatment. If the level is going down, the treatment is working. If it goes up, the cancer may be growing.

What is the normal range for AFP tumor marker?

An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).

What does AFP tumor marker test for?

Alpha-fetoprotein (AFP) is used as a tumor marker to help detect and diagnose cancers of the liver, testicles, and ovaries.