What is the survival rate of germ cell tumor?

The 5-year survival rate for teens ages 15 to 19 is 93%. The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%.

Are germ cell tumors cancerous?

Ovarian germ cell tumor is a disease in which malignant (cancer) cells form in the germ (egg) cells of the ovary. Germ cell tumors begin in the reproductive cells (egg or sperm) of the body. Ovarian germ cell tumors usually occur in teenage girls or young women and most often affect just one ovary.

How rare is a germ cell tumor?

Germ cell tumors are rare. Germ cell tumors account for about 2 to 4 percent of all cancers in children and adolescents younger than age 20. Germ cell tumors can spread (metastasize) to other parts of the body. The most common sites for metastasis are the lungs, liver, lymph nodes, and central nervous system.

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Can germ cell tumors come back?

How do providers treat benign (noncancerous) ovarian germ cell tumors? Healthcare providers remove benign tumors surgically. Sometimes, they need to remove the ovary (or part of the ovary) when removing the tumor. Benign tumors rarely grow back after providers remove them.

Is a germ cell tumor that grows quickly?

There are 2 different categories of germ cell tumors that start in the testicles or ovaries: seminomas and non-seminomas. Generally, non-seminomas tend to grow and spread more quickly than seminomas, but prompt diagnosis and treatment are important for both types of germ cell tumors.

Is germ cell tumor curable?

Germ cell tumors are relatively rare and represent a highly curable epithelial cancer. Optimal management of patients with germ cell tumors requires effective multidisciplinary management with medical oncology, urology, and in some instances, radiation oncology, working as a team.

What percentage of germ cell tumors are malignant?

Malignant germ cell tumors of the mediastinum are uncommon, representing only 3 to 10% of tumors originating in the mediastinum. They are much less common than germinal tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms.

Is Stage 4 germ cell tumor curable?

The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%. The cure rate for a stage IV tumor is 82%.

Where do germ cell tumors come from?

Germ cell tumors are growths of cells that form from reproductive cells. The tumors may be cancerous or not cancerous. Most germ cell tumors occur in the testicles or the ovaries. Some germ cell tumors occur in other areas of the body, such as the abdomen, brain and chest, though it’s not clear why.

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What are the signs of germ cell tumor?

Common signs of germ cell tumors include:

  • A mass on your ovaries or testicles.
  • Belly pain and swelling (caused by tumor)
  • Bathroom troubles (a hard time pooping or holding in your pee, if the tumor is near your pelvis)
  • Breast growth, pubic hair, or vaginal bleeding at an earlier age than normal.
  • Belly or chest pain.

How do you treat germ cell tumors?

Most patients with a cancerous germ cell tumor will need chemotherapy. The drugs that are commonly used for treating germ cell tumors include bleomycin (available as a generic drug), cisplatin (available as a generic drug), etoposide (Etopophos), and ifosfamide (Ifex).

Are germ cell tumors genetic?

The cause of germ cell tumors isn’t fully known. Some gene defects passed on from parents to children (inherited) may increase the risk for germ cell tumors. Some genetic syndromes can cause abnormal growth of the male and female reproductive systems.

Are Germinomas hereditary?

Although familial intracranial germ cell tumor is very rare, the fact that the parents of patients in previous and our reports had no abnormalities of possible hereditary origin suggests that these familial germ cell tumors might be an autosomal recessive disorder, as reported in the analysis of familial testicular …

What are the two types of germ cell tumors?

There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.

Does a teratoma need to be removed?

Teratomas are usually benign in newborns, but may still require surgical removal.

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Is sperm a germ cell?

​Germ Line

A germ line is the sex cells (eggs and sperm) that are used by sexually reproducing organisms to pass on genes from generation to generation. Egg and sperm cells are called germ cells, in contrast to the other cells of the body that are called somatic cells.