Can gefitinib cure lung cancer?

For non-small cell lung cancer (NSCLC) harboring activating EGFR mutations, tyrosine kinase inhibitors (TKIs) such as gefitinib are remarkably effective [1], and no cured case of advanced NSCLC has been reported yet.

Can gefitinib treat cancer?

Gefitinib is a treatment for non small cell lung cancer (NSCLC) that has spread into the surrounding tissues (locally advanced) or to other parts of the body. Gefitinib is also used in clinical trials for other cancer types.

How long can you take gefitinib?

“The patients taking gefitinib lived about 10 months longer without recurrence than patients who received chemotherapy, and patients are able to take [gefitinib] for almost 2 years and tolerate it very well,” Wu told HemOnc Today.

Can lung cancer go away?

For other people, lung cancer may never go away completely. Some people may get regular treatments with chemotherapy, radiation therapy, or other therapies to try to control the cancer for as long as possible. Learning to live with cancer that does not go away can be difficult and very stressful.

Is gefitinib a chemotherapy?

The use of cytotoxic chemotherapy is associated with a response rate of 20 to 35% and a median survival time of 10 to 12 months among patients with advanced non–small-cell lung cancer. Gefitinib is an orally administered tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR).

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What are the side effects of gefitinib?

Side Effects

  • Abdominal or stomach pain or tenderness.
  • clay colored stools.
  • decreased appetite.
  • diarrhea, severe.
  • itching or skin rash.
  • nausea and vomiting.
  • swelling of the feet or lower legs.
  • yellow eyes or skin.

What does gefitinib do to your body?

Gefitinib is used to treat lung cancer. It works by slowing or stopping the growth of cancer cells. Gefitinib blocks a certain protein (an enzyme called tyrosine kinase).

What is gefitinib used for?

Gefitinib is used to treat non-small cell lung cancer that has spread to other parts of the body in people with certain types of tumors. Gefitinib is in a class of medications called kinase inhibitors.

What is another name for gefitinib?

Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.


Clinical data
Trade names Iressa, others
Other names ZD1839
AHFS/ Monograph
MedlinePlus a607002

Can you live 20 years with lung cancer?

The NCI add that over half of people who receive a diagnosis of localized lung cancer will live for 5 years or longer following diagnosis. As diagnosis and treatment strategies improve, more people are surviving for a decade or longer with the condition.

Can you beat stage 4 lung cancer?

What Is Stage 4 Non-Small Cell Lung Cancer? Lynne Eldrige, MD, is a lung cancer physician, patient advocate, and award-winning author of “Avoiding Cancer One Day at a Time.” Doru Paul, MD, is triple board-certified in medical oncology, hematology, and internal medicine.

What stage of lung cancer is curable?

With early intervention, stage I lung cancer can be highly curable. Usually, your doctor will want to remove the cancer with surgery. You also may need chemo or radiation therapy if traces of cancer remain or are likely to stay.

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How is gefitinib administered?

Immerse IRESSA tablets in 4 to 8 ounces of water by dropping the tablet in water, and stir for approximately 15 minutes. Immediately drink the liquid or administer through a naso-gastric tube.

What is difference between erlotinib and gefitinib?

Gefitinib has been approved only for EGFR mutation bearing patients regardless the line of treatment, while erlotinib is also indicated in patients without EGFR mutation who undergo second- or third-line treatment.