What is the most important prognostic factor in breast cancer?

Involvement of axillary nodes has been the most important prognostic factor for breast cancer. Decisions regarding the use of adjuvant treatment in breast cancer have also largely been based on axillary node involvement.

What are the four most important prognostic factors for breast cancer?

Traditional prognostic factors, ie, those that predict the risk of recurrence or death from breast cancer, include number of positive axillary nodes, tumor size, tumor grade (histologic or nuclear), lymphatic and vascular invasion, and the estrogen-receptor (ER) and progesterone-receptor (PR) positivity.

What is the most important prognostic factor in cancer?

The most important prognostic factors include the following : Thickness and/or level of invasion. Mitotic index (mitoses per millimeter) Ulceration or bleeding at the primary site.

How is prognosis of breast cancer determined?

Doctors sometimes use online programs to estimate prognosis. The programs use information about the person and their breast cancer alongside data from large research studies. The results are often presented, in the form of graphs, as a percentage survival rate at five and/or ten years after diagnosis.

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What is prognostic factor?

Listen to pronunciation. (prog-NOS-tik FAK-ter) A situation or condition, or a characteristic of a patient, that can be used to estimate the chance of recovery from a disease or the chance of the disease recurring (coming back).

What prognostic means?

1 : something that foretells : portent. 2 : prognostication, prophecy. prognostic.

What are positive prognostic factors?

Prognostic or predictive factors may include patient characteristics such as age, ethnicity, sex, or smoking status, disease characteristics such as disease stage or nodal status, and molecular markers such as HER2 amplification and K ras mutation.

What are poor prognostic factors?

Poor prognostic factors include the stage of disease at presentation, which is influenced by presence of nodal and/or distant disease. In particular, the presence of nodal disease influences survival and the likelihood of metastatic disease.

What is the most important prognostic factor for human cancer is proved to be of greater clinical value?

Prognostic Factors

The most important prognostic factor in all human cancers is the stage at presentation, which is the anatomic extent of the disease.

What good prognosis means?

A favorable prognosis means a good chance of treatment success. For example, the overall 5-year relative survival rate for testicular cancer is 95%. This means that most men diagnosed with the disease have a favorable prognosis.

What does a good prognosis for breast cancer mean?

Many people live much longer than 5 years after being diagnosed. It’s also important to remember that people diagnosed with breast cancer can die from other causes — stroke or heart attack, for example.

What Does Prognosis Mean?

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Breast Cancer Stage 5-Year Relative Survival Rate for Men
I 100%
II 91%
III 72%
IV 20%

What is your prognosis?

Byock: Prognosis is a term for the predicted course of a disease. People commonly use the word to refer to an individual’s life expectancy, how long the person is likely to live.

What is prognostic factors in clinical trials?

Prognostic factors define the study population, help formulate the study objectives, and influence the treatment strategies. They must be accounted for in the study analysis to obtain valid estimates of the treatment differences and to evaluate results across studies.

What are predictive and prognostic factors?

We defined a prognostic factor as a patient characteristic that identifies subgroups of untreated patients having different outcomes, and a factor predictive of treatment effect as a patient characteristic that identifies subgroups of treated patients having different (as a consequence of treatment) outcomes.

What are prognostic factors in research?

A prognostic factor is any variable that is associated with the risk of a subsequent health outcome among people with a particular health condition. Different values or categories of a prognostic factor are associated with a better or worse prognosis of future health outcomes.